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Over supplementation with vitamin B12 alters microbe-host interactions in the gut leading to accelerated Citrobacter rodentium colonization and pathogenesis in mice

BACKGROUND: Vitamin B12 supplements typically contain doses that far exceed the recommended daily amount, and high exposures are generally considered safe. Competitive and syntrophic interactions for B12 exist between microbes in the gut. Yet, to what extent excessive levels contribute to the activi...

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Detalles Bibliográficos
Autores principales: Forgie, Andrew J., Pepin, Deanna M., Ju, Tingting, Tollenaar, Stephanie, Sergi, Consolato M., Gruenheid, Samantha, Willing, Benjamin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896722/
https://www.ncbi.nlm.nih.gov/pubmed/36737826
http://dx.doi.org/10.1186/s40168-023-01461-w