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Targeting high glucose-induced epigenetic modifications at cardiac level: the role of SGLT2 and SGLT2 inhibitors

BACKGROUND: Sodium-glucose co-transporters (SGLT) inhibitors (SGLT2i) showed many beneficial effects at the cardiovascular level. Several mechanisms of action have been identified. However, no data on their capability to act via epigenetic mechanisms were reported. Therefore, this study aimed to inv...

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Detalles Bibliográficos
Autores principales: Scisciola, Lucia, Taktaz, Fatemeh, Fontanella, Rosaria Anna, Pesapane, Ada, Surina, Cataldo, Vittoria, Ghosh, Puja, Franzese, Martina, Puocci, Armando, Paolisso, Pasquale, Rafaniello, Concetta, Marfella, Raffaele, Rizzo, Maria Rosaria, Barbato, Emanuele, Vanderheyden, Marc, Barbieri, Michelangela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896756/
https://www.ncbi.nlm.nih.gov/pubmed/36732760
http://dx.doi.org/10.1186/s12933-023-01754-2