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Plasma extracellular vesicle messenger RNA profiling identifies prognostic EV signature for non-invasive risk stratification for survival prediction of patients with pancreatic ductal adenocarcinoma

BACKGROUND: The prognosis of pancreatic ductal adenocarcinoma (PDAC) is one of the most dismal of all cancers and the median survival of PDAC patients is only 6–8 months after diagnosis. While decades of research effort have been focused on early diagnosis and understanding of molecular mechanisms,...

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Detalles Bibliográficos
Autores principales: Han, Yi, Drobisch, Pascal, Krüger, Alexander, William, Doreen, Grützmann, Konrad, Böthig, Lukas, Polster, Heike, Seifert, Lena, Seifert, Adrian M., Distler, Marius, Pecqueux, Mathieu, Riediger, Carina, Plodeck, Verena, Nebelung, Heiner, Weber, Georg F., Pilarsky, Christian, Kahlert, Ulf, Hinz, Ulf, Roth, Susanne, Hackert, Thilo, Weitz, Jürgen, Wong, Fang Cheng, Kahlert, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896775/
https://www.ncbi.nlm.nih.gov/pubmed/36737824
http://dx.doi.org/10.1186/s13045-023-01404-w