VEGF-A enhances the cytotoxic function of CD4(+) cytotoxic T cells via the VEGF-receptor 1/VEGF-receptor 2/AKT/mTOR pathway

BACKGROUND: CD4(+) cytotoxic T cells (CD4 CTLs) are CD4(+) T cells with major histocompatibility complex-II-restricted cytotoxic function. Under pathologic conditions, CD4 CTLs hasten the development of autoimmune disease or viral infection by enhancing cytotoxicity. However, the regulators of the c...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Ziyi, Zhang, Meng, Liu, Yufeng, Chen, Zhe, Wang, Ling, Wang, Wenjuan, Wang, Jincheng, He, Mingqian, Shi, Bingyin, Wang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896805/
https://www.ncbi.nlm.nih.gov/pubmed/36737819
http://dx.doi.org/10.1186/s12967-023-03926-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896805/
https://www.ncbi.nlm.nih.gov/pubmed/36737819
http://dx.doi.org/10.1186/s12967-023-03926-w

Ejemplares similares