Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition

BACKGROUND: Recurrence due to the development of radioresistance remains a major challenge in the clinical management of nasopharyngeal carcinoma. The objective of this study was to increase the sensitivity of nasopharyngeal carcinoma cells to ionizing radiation by enhancing oxidative stress and fer...

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Detalles Bibliográficos
Autores principales: Amos, Alvan, Jiang, Ning, Zong, Dan, Gu, Jiajia, Zhou, Jiawei, Yin, Li, He, Xia, Xu, Yong, Wu, Lirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896811/
https://www.ncbi.nlm.nih.gov/pubmed/36737723
http://dx.doi.org/10.1186/s12885-022-10465-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896811/
https://www.ncbi.nlm.nih.gov/pubmed/36737723
http://dx.doi.org/10.1186/s12885-022-10465-y

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