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Emergent expression of fitness-conferring genes by phenotypic selection

Genotypic and phenotypic adaptation is the consequence of ongoing natural selection in populations and is key to predicting and preventing drug resistance. Whereas classic antibiotic persistence is all-or-nothing, here we demonstrate that an antibiotic resistance gene displays linear dose-responsive...

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Detalles Bibliográficos
Autores principales: Ciechonska, Marta, Sturrock, Marc, Grob, Alice, Larrouy-Maumus, Gerald, Shahrezaei, Vahid, Isalan, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896880/
https://www.ncbi.nlm.nih.gov/pubmed/36741458
http://dx.doi.org/10.1093/pnasnexus/pgac069