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Emergent expression of fitness-conferring genes by phenotypic selection
Genotypic and phenotypic adaptation is the consequence of ongoing natural selection in populations and is key to predicting and preventing drug resistance. Whereas classic antibiotic persistence is all-or-nothing, here we demonstrate that an antibiotic resistance gene displays linear dose-responsive...
Autores principales: | Ciechonska, Marta, Sturrock, Marc, Grob, Alice, Larrouy-Maumus, Gerald, Shahrezaei, Vahid, Isalan, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896880/ https://www.ncbi.nlm.nih.gov/pubmed/36741458 http://dx.doi.org/10.1093/pnasnexus/pgac069 |
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