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Signatures of muscle disuse in spaceflight and bed rest revealed by single muscle fiber proteomics

Astronauts experience dramatic loss of muscle mass, decreased strength, and insulin resistance, despite performing daily intense physical exercise that would lead to muscle growth on Earth. Partially mimicking spaceflight, prolonged bed rest causes muscle atrophy, loss of force, and glucose intolera...

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Detalles Bibliográficos
Autores principales: Murgia, Marta, Ciciliot, Stefano, Nagaraj, Nagarjuna, Reggiani, Carlo, Schiaffino, Stefano, Franchi, Martino V, Pišot, Rado, Šimunič, Boštjan, Toniolo, Luana, Blaauw, Bert, Sandri, Marco, Biolo, Gianni, Flück, Martin, Narici, Marco V, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896895/
https://www.ncbi.nlm.nih.gov/pubmed/36741463
http://dx.doi.org/10.1093/pnasnexus/pgac086