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Signatures of muscle disuse in spaceflight and bed rest revealed by single muscle fiber proteomics
Astronauts experience dramatic loss of muscle mass, decreased strength, and insulin resistance, despite performing daily intense physical exercise that would lead to muscle growth on Earth. Partially mimicking spaceflight, prolonged bed rest causes muscle atrophy, loss of force, and glucose intolera...
Autores principales: | Murgia, Marta, Ciciliot, Stefano, Nagaraj, Nagarjuna, Reggiani, Carlo, Schiaffino, Stefano, Franchi, Martino V, Pišot, Rado, Šimunič, Boštjan, Toniolo, Luana, Blaauw, Bert, Sandri, Marco, Biolo, Gianni, Flück, Martin, Narici, Marco V, Mann, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896895/ https://www.ncbi.nlm.nih.gov/pubmed/36741463 http://dx.doi.org/10.1093/pnasnexus/pgac086 |
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