Association of CSF Glucocerebrosidase Activity With the Risk of Incident Dementia in Patients With Parkinson Disease

BACKGROUND AND OBJECTIVES: Variations in the glucocerebrosidase gene (GBA) are common risk factors for Parkinson disease (PD) and dementia in PD (PDD) and cause a reduction in the activity of the lysosomal enzyme glucocerebrosidase (GCase). It is anticipated that GCase dysfunction might contribute t...

Descripción completa

Detalles Bibliográficos
Autores principales: Oftedal, Linn, Maple-Grødem, Jodi, Dalen, Ingvild, Tysnes, Ole-Bjørn, Pedersen, Kenn Freddy, Alves, Guido, Lange, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897053/
https://www.ncbi.nlm.nih.gov/pubmed/36253102
http://dx.doi.org/10.1212/WNL.0000000000201418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897053/
https://www.ncbi.nlm.nih.gov/pubmed/36253102
http://dx.doi.org/10.1212/WNL.0000000000201418

Ejemplares similares