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Transcriptional Plasticity Drives Leukemia Immune Escape

Relapse of acute myeloid leukemia (AML) after allogeneic bone marrow transplantation has been linked to immune evasion due to reduced expression of major histocompatibility complex class II (MHCII) genes through unknown mechanisms. In this work, we developed CORENODE, a computational algorithm for g...

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Detalles Bibliográficos
Autores principales: Eagle, Kenneth, Harada, Taku, Kalfon, Jérémie, Perez, Monika W., Heshmati, Yaser, Ewers, Jazmin, Koren, Jošt Vrabič, Dempster, Joshua M., Kugener, Guillaume, Paralkar, Vikram R., Lin, Charles Y., Dharia, Neekesh V., Stegmaier, Kimberly, Orkin, Stuart H., Pimkin, Maxim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897290/
https://www.ncbi.nlm.nih.gov/pubmed/35709529
http://dx.doi.org/10.1158/2643-3230.BCD-21-0207