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Transcriptional Plasticity Drives Leukemia Immune Escape
Relapse of acute myeloid leukemia (AML) after allogeneic bone marrow transplantation has been linked to immune evasion due to reduced expression of major histocompatibility complex class II (MHCII) genes through unknown mechanisms. In this work, we developed CORENODE, a computational algorithm for g...
Autores principales: | Eagle, Kenneth, Harada, Taku, Kalfon, Jérémie, Perez, Monika W., Heshmati, Yaser, Ewers, Jazmin, Koren, Jošt Vrabič, Dempster, Joshua M., Kugener, Guillaume, Paralkar, Vikram R., Lin, Charles Y., Dharia, Neekesh V., Stegmaier, Kimberly, Orkin, Stuart H., Pimkin, Maxim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897290/ https://www.ncbi.nlm.nih.gov/pubmed/35709529 http://dx.doi.org/10.1158/2643-3230.BCD-21-0207 |
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