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CREBB repression of protein synthesis in mushroom body gates long-term memory formation in Drosophila

Learned experiences are not necessarily consolidated into long-term memory (LTM) unless they are periodic and meaningful. LTM depends on de novo protein synthesis mediated by cyclic AMP response element-binding protein (CREB) activity. In Drosophila, two creb genes (crebA, crebB) and multiple CREB i...

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Detalles Bibliográficos
Autores principales: Lin, Hsuan-Wen, Chen, Chun-Chao, Jhang, Ruei-Yu, Chen, Linyi, de Belle, J. Steven, Tully, Tim, Chiang, Ann-Shyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897441/
https://www.ncbi.nlm.nih.gov/pubmed/36469774
http://dx.doi.org/10.1073/pnas.2211308119