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CREBB repression of protein synthesis in mushroom body gates long-term memory formation in Drosophila
Learned experiences are not necessarily consolidated into long-term memory (LTM) unless they are periodic and meaningful. LTM depends on de novo protein synthesis mediated by cyclic AMP response element-binding protein (CREB) activity. In Drosophila, two creb genes (crebA, crebB) and multiple CREB i...
Autores principales: | Lin, Hsuan-Wen, Chen, Chun-Chao, Jhang, Ruei-Yu, Chen, Linyi, de Belle, J. Steven, Tully, Tim, Chiang, Ann-Shyn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897441/ https://www.ncbi.nlm.nih.gov/pubmed/36469774 http://dx.doi.org/10.1073/pnas.2211308119 |
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