Bioengineered peptibodies as blockers of ion channels

We engineered and produced an ion channel blocking peptibody, that targets the acetylcholine-activated inwardly rectifying potassium current (I(KACh)). Peptibodies are chimeric proteins generated by fusing a biologically active peptide with the fragment crystallizable (Fc) region of the human immuno...

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Detalles Bibliográficos
Autores principales: Chidipi, Bojjibabu, Chang, Mengmeng, Cui, Meng, Abou-Assali, Obada, Reiser, Michelle, Pshenychnyi, Sergii, Logothetis, Diomedes E., Teng, Michael N., Noujaim, Sami F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897444/
https://www.ncbi.nlm.nih.gov/pubmed/36475947
http://dx.doi.org/10.1073/pnas.2212564119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897444/
https://www.ncbi.nlm.nih.gov/pubmed/36475947
http://dx.doi.org/10.1073/pnas.2212564119

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