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APC couples neuronal mRNAs to multiple kinesins, EB1, and shrinking microtubule ends for bidirectional mRNA motility

Understanding where in the cytoplasm mRNAs are translated is increasingly recognized as being as important as knowing the timing and level of protein expression. mRNAs are localized via active motor-driven transport along microtubules (MTs) but the underlying essential factors and dynamic interactio...

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Detalles Bibliográficos
Autores principales: Baumann, Sebastian J., Grawenhoff, Julia, Rodrigues, Elsa C., Speroni, Silvia, Gili, Maria, Komissarov, Artem, Maurer, Sebastian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897468/
https://www.ncbi.nlm.nih.gov/pubmed/36469763
http://dx.doi.org/10.1073/pnas.2211536119