Cargando…
In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation
Mammalian reovirus (reovirus) is a multilayered, turreted member of Reoviridae characterized by transcription of dsRNA genome within the innermost capsid shell. Here, we present high-resolution in situ structures of reovirus transcriptase complex in an intact double-layered virion, and in the uncoat...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897473/ https://www.ncbi.nlm.nih.gov/pubmed/36469786 http://dx.doi.org/10.1073/pnas.2203054119 |