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Biophysical characterization of calcium-binding and modulatory-domain dynamics in a pentameric ligand-gated ion channel

Pentameric ligand-gated ion channels (pLGICs) perform electrochemical signal transduction in organisms ranging from bacteria to humans. Among the prokaryotic pLGICs, there is architectural diversity involving N-terminal domains (NTDs) not found in eukaryotic relatives, exemplified by the calcium-sen...

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Detalles Bibliográficos
Autores principales: Lycksell, Marie, Rovšnik, Urška, Hanke, Anton, Martel, Anne, Howard, Rebecca J., Lindahl, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897478/
https://www.ncbi.nlm.nih.gov/pubmed/36480474
http://dx.doi.org/10.1073/pnas.2210669119