Recruitment of CTCF to an Fto enhancer is responsible for transgenerational inheritance of BPA-induced obesity

The mechanisms by which environmentally-induced epiphenotypes are transmitted transgenerationally in mammals are poorly understood. Here we show that exposure of pregnant mouse females to bisphenol A (BPA) results in obesity in the F2 progeny due to increased food intake. This epiphenotype can be tr...

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Detalles Bibliográficos
Autores principales: Jung, Yoon Hee, Wang, Hsiao-Lin V., Ruiz, Daniel, Bixler, Brianna J., Linsenbaum, Hannah, Xiang, Jian-Feng, Forestier, Samantha, Shafik, Andrew M., Jin, Peng, Corces, Victor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897486/
https://www.ncbi.nlm.nih.gov/pubmed/36469784
http://dx.doi.org/10.1073/pnas.2214988119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897486/
https://www.ncbi.nlm.nih.gov/pubmed/36469784
http://dx.doi.org/10.1073/pnas.2214988119

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