Cargando…
Recruitment of CTCF to an Fto enhancer is responsible for transgenerational inheritance of BPA-induced obesity
The mechanisms by which environmentally-induced epiphenotypes are transmitted transgenerationally in mammals are poorly understood. Here we show that exposure of pregnant mouse females to bisphenol A (BPA) results in obesity in the F2 progeny due to increased food intake. This epiphenotype can be tr...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897486/ https://www.ncbi.nlm.nih.gov/pubmed/36469784 http://dx.doi.org/10.1073/pnas.2214988119 |