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Bayesian mixed model analysis uncovered 21 risk loci for chronic kidney disease in boxer dogs

Chronic kidney disease (CKD) affects 10% of the human population, with only a small fraction genetically defined. CKD is also common in dogs and has been diagnosed in nearly all breeds, but its genetic basis remains unclear. Here, we performed a Bayesian mixed model genome-wide association analysis...

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Detalles Bibliográficos
Autores principales: Lingaas, Frode, Tengvall, Katarina, Jansen, Johan Høgset, Pelander, Lena, Hurst, Maria H., Meuwissen, Theo, Karlsson, Åsa, Meadows, Jennifer R. S., Sundström, Elisabeth, Thoresen, Stein Istre, Arnet, Ellen Frøysadal, Guttersrud, Ole Albert, Kierczak, Marcin, Hytönen, Marjo K., Lohi, Hannes, Hedhammar, Åke, Lindblad-Toh, Kerstin, Wang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897549/
https://www.ncbi.nlm.nih.gov/pubmed/36693108
http://dx.doi.org/10.1371/journal.pgen.1010599