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Cancer stem cell-derived extracellular vesicles preferentially target MHC-II–macrophages and PD1+ T cells in the tumor microenvironment

Immunotherapy is an approved treatment option for head and neck squamous cell carcinoma (HNSCC). However, the response rate to immune checkpoint blockade is only 13% for recurrent HNSCC, highlighting the urgent need to better understand tumor-immune interplay, with the ultimate goal of improving pat...

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Detalles Bibliográficos
Autores principales: Gonzalez-Callejo, Patricia, Guo, Zihan, Ziglari, Tahereh, Claudio, Natalie Marcia, Nguyen, Kayla Hoang, Oshimori, Naoki, Seras-Franzoso, Joaquim, Pucci, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897575/
https://www.ncbi.nlm.nih.gov/pubmed/36735677
http://dx.doi.org/10.1371/journal.pone.0279400