SSRIs differentially modulate the effects of pro-inflammatory stimulation on hippocampal plasticity and memory via sigma 1 receptors and neurosteroids

Certain selective serotonin reuptake inhibitors (SSRIs) have anti-inflammatory effects in preclinical models, and recent clinical studies suggest that fluvoxamine can prevent deterioration in patients with COVID-19, possibly through activating sigma 1 receptors (S1Rs). Here we examined potential mec...

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Detalles Bibliográficos
Autores principales: Izumi, Yukitoshi, Reiersen, Angela M., Lenze, Eric J., Mennerick, Steven J., Zorumski, Charles F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897619/
https://www.ncbi.nlm.nih.gov/pubmed/36737431
http://dx.doi.org/10.1038/s41398-023-02343-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897619/
https://www.ncbi.nlm.nih.gov/pubmed/36737431
http://dx.doi.org/10.1038/s41398-023-02343-3

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