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Integration of network pharmacology and intestinal flora to investigate the mechanism of action of Chinese herbal Cichorium intybus formula in attenuating adenine and ethambutol hydrochloride-induced hyperuricemic nephropathy in rats

CONTEXT: Cichorium intybus L. (Asteraceae) formula (CF) has been applied as a folk medicine to treat hyperuricemic nephropathy (HN). However, the exact mechanism remains unclear. OBJECTIVE: To explore the therapeutic effect and mechanism of CF on HN. MATERIALS AND METHODS: Through network pharmacolo...

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Detalles Bibliográficos
Autores principales: Li, Na, Amatjan, Mukaram, He, Pengke, Zhang, Boheng, Mai, Xianyan, Jiang, Qianle, Xie, Haochen, Shao, Xiaoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897651/
https://www.ncbi.nlm.nih.gov/pubmed/36444935
http://dx.doi.org/10.1080/13880209.2022.2147551