Beta human papillomavirus 8E6 promotes alternative end joining

Double strand breaks (DSBs) are one of the most lethal DNA lesions in cells. The E6 protein of beta-human papillomavirus (HPV8 E6) impairs two critical DSB repair pathways: homologous recombination (HR) and non-homologous end joining (NHEJ). However, HPV8 E6 only delays DSB repair. How DSBs are repa...

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Detalles Bibliográficos
Autores principales: Hu, Changkun, Bugbee, Taylor, Palinski, Rachel, Akinyemi, Ibukun A, McIntosh, Michael T, MacCarthy, Thomas, Bhaduri-McIntosh, Sumita, Wallace, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897725/
https://www.ncbi.nlm.nih.gov/pubmed/36692284
http://dx.doi.org/10.7554/eLife.81923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897725/
https://www.ncbi.nlm.nih.gov/pubmed/36692284
http://dx.doi.org/10.7554/eLife.81923

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