Discovery of novel 2-(4-(benzyloxy)-5-(hydroxyl) phenyl) benzothiazole derivatives as multifunctional MAO-B inhibitors for the treatment of Parkinson’s disease

To discover novel multifunctional agents for the treatment of Parkinson’s disease, a series of 2-(4-(benzyloxy)-5-(hydroxyl) phenyl) benzothiazole derivatives was designed, synthesized and evaluated. The results revealed that representative compound 3h possessed potent and selective MAO-B inhibitory...

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Detalles Bibliográficos
Autores principales: Cao, Zhongcheng, Wang, Xingyue, Zhang, Tianlong, Fu, Xianwu, Zhang, Fan, Zhu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897792/
https://www.ncbi.nlm.nih.gov/pubmed/36728713
http://dx.doi.org/10.1080/14756366.2022.2159957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897792/
https://www.ncbi.nlm.nih.gov/pubmed/36728713
http://dx.doi.org/10.1080/14756366.2022.2159957

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