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Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia

Nuclear factor I-C (NFIC) belongs to a family of NFI transcription factors that binds to DNA through CAATT-boxes and are involved in cellular differentiation and stem cell maintenance. Here we show NFIC protein is significantly overexpressed in 69% of acute myeloid leukemia patients. Examination of...

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Detalles Bibliográficos
Autores principales: Rastogi, Namrata, Gonzalez, Juan Bautista Menendez, Srivastava, Vikas Kumar, Alanazi, Bader, Alanazi, Rehab N., Hughes, Owen M., O’Neill, Niamh S., Gilkes, Amanda F., Ashley, Neil, Deshpande, Sumukh, Andrews, Robert, Mead, Adam, Rodrigues, Neil P., Knapper, Steve, Darley, Richard L., Tonks, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898032/
https://www.ncbi.nlm.nih.gov/pubmed/36572750
http://dx.doi.org/10.1038/s41375-022-01801-z