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Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia
Nuclear factor I-C (NFIC) belongs to a family of NFI transcription factors that binds to DNA through CAATT-boxes and are involved in cellular differentiation and stem cell maintenance. Here we show NFIC protein is significantly overexpressed in 69% of acute myeloid leukemia patients. Examination of...
Autores principales: | Rastogi, Namrata, Gonzalez, Juan Bautista Menendez, Srivastava, Vikas Kumar, Alanazi, Bader, Alanazi, Rehab N., Hughes, Owen M., O’Neill, Niamh S., Gilkes, Amanda F., Ashley, Neil, Deshpande, Sumukh, Andrews, Robert, Mead, Adam, Rodrigues, Neil P., Knapper, Steve, Darley, Richard L., Tonks, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898032/ https://www.ncbi.nlm.nih.gov/pubmed/36572750 http://dx.doi.org/10.1038/s41375-022-01801-z |
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