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Targeting PEA3 transcription factors to mitigate small cell lung cancer progression

Small cell lung cancer (SCLC) remains a lethal disease with a dismal overall survival rate of 6% despite promising responses to upfront combination chemotherapy. The key drivers of such rapid mortality include early metastatic dissemination in the natural course of the disease and the near guarantee...

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Detalles Bibliográficos
Autores principales: Shia, David W., Choi, WooSuk, Vijayaraj, Preethi, Vuong, Valarie, Sandlin, Jenna M., Lu, Michelle M., Aziz, Adam, Marin, Caliope, Aros, Cody J., Sen, Chandani, Durra, Abdo, Lund, Andrew J., Purkayastha, Arunima, Rickabaugh, Tammy M., Graeber, Thomas G., Gomperts, Brigitte N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898033/
https://www.ncbi.nlm.nih.gov/pubmed/36509998
http://dx.doi.org/10.1038/s41388-022-02558-6