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Transient regulation of RNA methylation in human hematopoietic stem cells promotes their homing and engraftment

Enhancing the efficiency of hematopoietic stem cell (HSC) homing and engraftment is critical for cord blood (CB) hematopoietic cell transplantation (HCT). Recent studies indicate that N(6)-methyladenosine (m(6)A) modulates the expression of mRNAs that are critical for stem cell function by influenci...

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Detalles Bibliográficos
Autores principales: Wang, Xuepeng, Cooper, Scott, Broxmeyer, Hal E., Kapur, Reuben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898034/
https://www.ncbi.nlm.nih.gov/pubmed/36460765
http://dx.doi.org/10.1038/s41375-022-01761-4