Cargando…
Transient regulation of RNA methylation in human hematopoietic stem cells promotes their homing and engraftment
Enhancing the efficiency of hematopoietic stem cell (HSC) homing and engraftment is critical for cord blood (CB) hematopoietic cell transplantation (HCT). Recent studies indicate that N(6)-methyladenosine (m(6)A) modulates the expression of mRNAs that are critical for stem cell function by influenci...
Autores principales: | Wang, Xuepeng, Cooper, Scott, Broxmeyer, Hal E., Kapur, Reuben |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898034/ https://www.ncbi.nlm.nih.gov/pubmed/36460765 http://dx.doi.org/10.1038/s41375-022-01761-4 |
Ejemplares similares
-
Nuclear translocation of TFE3 under hypoxia enhances the engraftment of human hematopoietic stem cells
por: Wang, Xuepeng, et al.
Publicado: (2022) -
Quickly attainable and highly engrafting hematopoietic stem cells
por: Broxmeyer, Hal E.
Publicado: (2019) -
Neutralizing negative epigenetic regulation by HDAC5 enhances human haematopoietic stem cell homing and engraftment
por: Huang, Xinxin, et al.
Publicado: (2018) -
Physioxia-induced downregulation of Tet2 in hematopoietic stem cells contributes to enhanced self-renewal
por: Aljoufi, Arafat, et al.
Publicado: (2022) -
Transient Inhibition of the JNK Pathway Promotes Human Hematopoietic Stem Cell Quiescence and Engraftment
por: Xie, Huangfan, et al.
Publicado: (2022)