L3MBTL3 is induced by HIF-1α and fine tunes the HIF-1α degradation under hypoxia in vitro

HIF-1α plays a crucial part in hypoxia response by transcriptionally upregulating genes to adapt the hypoxic condition. HIF-1α is under severe cellular control as its exceptional activation is always associated with tumorigenesis and tumor progression. Here, we report L3MBTL3 serves as a novel negat...

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Detalles Bibliográficos
Autores principales: Wang, Mengdong, Wang, Di, Lang, Yue, Shao, Anwen, Zhang, Rui, Tang, Jun, Lai, Dongming, Xiao, Chenglu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898070/
https://www.ncbi.nlm.nih.gov/pubmed/36747531
http://dx.doi.org/10.1016/j.heliyon.2023.e13222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898070/
https://www.ncbi.nlm.nih.gov/pubmed/36747531
http://dx.doi.org/10.1016/j.heliyon.2023.e13222

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