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L3MBTL3 is induced by HIF-1α and fine tunes the HIF-1α degradation under hypoxia in vitro
HIF-1α plays a crucial part in hypoxia response by transcriptionally upregulating genes to adapt the hypoxic condition. HIF-1α is under severe cellular control as its exceptional activation is always associated with tumorigenesis and tumor progression. Here, we report L3MBTL3 serves as a novel negat...
Autores principales: | Wang, Mengdong, Wang, Di, Lang, Yue, Shao, Anwen, Zhang, Rui, Tang, Jun, Lai, Dongming, Xiao, Chenglu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898070/ https://www.ncbi.nlm.nih.gov/pubmed/36747531 http://dx.doi.org/10.1016/j.heliyon.2023.e13222 |
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