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Cocaine self-administration augments kappa opioid receptor system-mediated inhibition of dopamine activity in the mesolimbic dopamine system

Prior studies examining the effects of cocaine on the dynorphin/kappa opioid receptor (Dyn/KOR) system primarily focus on non-contingent cocaine exposure, but the effects of self-administration, which more closely reflects human drug-taking behaviors, are not well studied. In this study we character...

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Detalles Bibliográficos
Autores principales: Estave, Paige M., Sun, Haiguo, Peck, Emily G., Holleran, Katherine M., Chen, Rong, Jones, Sara R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898071/
https://www.ncbi.nlm.nih.gov/pubmed/36748012
http://dx.doi.org/10.1016/j.ibneur.2023.01.004