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Catecholamine induces Kupffer cell apoptosis via growth differentiation factor 15 in alcohol-associated liver disease

Chronic alcohol consumption often induces hepatic steatosis but rarely causes severe inflammation in Kupffer cells (KCs) despite the increased hepatic influx of lipopolysaccharide (LPS), suggesting the presence of a veiled tolerance mechanism. In addition to LPS, the liver is affected by several gut...

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Detalles Bibliográficos
Autores principales: Kim, Hee-Hoon, Shim, Young-Ri, Choi, Sung Eun, Kim, Myung-Ho, Lee, Giljae, You, Hyun Ju, Choi, Won-Mook, Yang, Keungmo, Ryu, Tom, Kim, Kyurae, Kim, Min Jeong, Woo, Chaerin, Chung, Katherine Po Sin, Hong, Song Hwa, Eun, Hyuk Soo, Kim, Seok-Hwan, Ko, GwangPyo, Park, Jong-Eun, Gao, Bin, Kim, Won, Jeong, Won-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898237/
https://www.ncbi.nlm.nih.gov/pubmed/36631664
http://dx.doi.org/10.1038/s12276-022-00921-x