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On the interplay between lipids and asymmetric dynamics of an NBS degenerate ABC transporter

Multidrug resistance-associated proteins are ABC C-family exporters. They are crucial in pharmacology as they transport various substrates across membranes. However, the role of the degenerate nucleotide-binding site (NBS) remains unclear likewise the interplay with the surrounding lipid environment...

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Detalles Bibliográficos
Autores principales: Tóth, Ágota, Janaszkiewicz, Angelika, Crespi, Veronica, Di Meo, Florent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898250/
https://www.ncbi.nlm.nih.gov/pubmed/36737455
http://dx.doi.org/10.1038/s42003-023-04537-3