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On the interplay between lipids and asymmetric dynamics of an NBS degenerate ABC transporter
Multidrug resistance-associated proteins are ABC C-family exporters. They are crucial in pharmacology as they transport various substrates across membranes. However, the role of the degenerate nucleotide-binding site (NBS) remains unclear likewise the interplay with the surrounding lipid environment...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898250/ https://www.ncbi.nlm.nih.gov/pubmed/36737455 http://dx.doi.org/10.1038/s42003-023-04537-3 |