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Cdon suppresses vascular smooth muscle calcification via repression of the Wnt/Runx2 Axis
Osteogenic transdifferentiation of vascular smooth muscle cells (VSMCs) is a risk factor associated with vascular diseases. Wnt signaling is one of the major mechanisms implicated in the osteogenic conversion of VSMCs. Since Cdon has a negative effect on Wnt signaling in distinct cellular processes,...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898282/ https://www.ncbi.nlm.nih.gov/pubmed/36609601 http://dx.doi.org/10.1038/s12276-022-00909-7 |