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Cdon suppresses vascular smooth muscle calcification via repression of the Wnt/Runx2 Axis

Osteogenic transdifferentiation of vascular smooth muscle cells (VSMCs) is a risk factor associated with vascular diseases. Wnt signaling is one of the major mechanisms implicated in the osteogenic conversion of VSMCs. Since Cdon has a negative effect on Wnt signaling in distinct cellular processes,...

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Detalles Bibliográficos
Autores principales: Ahn, Byeong-Yun, Jeong, Yideul, Kim, Sunghee, Zhang, Yan, Kim, Su Woo, Leem, Young-Eun, Kang, Jong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898282/
https://www.ncbi.nlm.nih.gov/pubmed/36609601
http://dx.doi.org/10.1038/s12276-022-00909-7