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USP15 promotes pulmonary vascular remodeling in pulmonary hypertension in a YAP1/TAZ-dependent manner

Pulmonary hypertension (PH) is a life-threatening cardiopulmonary disease characterized by pulmonary vascular remodeling. Excessive growth and migration of pulmonary artery smooth muscle cells (PASMCs) are believed to be major contributors to pulmonary vascular remodeling. Ubiquitin-specific proteas...

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Detalles Bibliográficos
Autores principales: Wu, Zhuhua, Zhu, Li, Nie, Xinran, Wei, Li, Qi, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898287/
https://www.ncbi.nlm.nih.gov/pubmed/36635430
http://dx.doi.org/10.1038/s12276-022-00920-y