TPX2 prompts mitotic survival via the induction of BCL2L1 through YAP1 protein stabilization in human embryonic stem cells

Genetic alterations have been reported for decades in most human embryonic stem cells (hESCs). Survival advantage, a typical trait acquired during long-term in vitro culture, results from the induction of BCL2L1 upon frequent copy number variation (CNV) at locus 20q11.21 and is one of the strongest...

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Detalles Bibliográficos
Autores principales: Kim, Yun-Jeong, Go, Young-Hyun, Jeong, Ho-Chang, Kwon, Eun-Ji, Kim, Seong-Min, Cheong, Hyun Sub, Kim, Wantae, Shin, Hyoung Doo, Lee, Haeseung, Cha, Hyuk-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898288/
https://www.ncbi.nlm.nih.gov/pubmed/36596852
http://dx.doi.org/10.1038/s12276-022-00907-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898288/
https://www.ncbi.nlm.nih.gov/pubmed/36596852
http://dx.doi.org/10.1038/s12276-022-00907-9

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