Leflunomide abrogates neuroinflammatory changes in a rat model of Alzheimer’s disease: the role of TNF-α/NF-κB/IL-1β axis inhibition

Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases and is associated with disrupted cognition and behavior. Neuroinflammatory pathogenesis is the main component that contributes to AD initiation and progression through microglial activation and neuronal damage. Thus, targe...

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Detalles Bibliográficos
Autores principales: Nafea, Menna, Elharoun, Mona, Abd-Alhaseeb, Mohammad Mohmoud, Helmy, Maged Wasfy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898334/
https://www.ncbi.nlm.nih.gov/pubmed/36385687
http://dx.doi.org/10.1007/s00210-022-02322-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898334/
https://www.ncbi.nlm.nih.gov/pubmed/36385687
http://dx.doi.org/10.1007/s00210-022-02322-3

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