Cargando…

PITX1 suppresses osteosarcoma metastasis through exosomal LINC00662-mediated M2 macrophage polarization

Paired-like homeodomain transcription factor 1 (PITX1) is frequently downregulated in cancers, including osteosarcoma (OS). However, its role in OS remains unknown. Therefore, we aimed to explore the functions and potential mechanisms of PITX1 in OS malignant progression. Elevated PITX1 suppressed O...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Ying, Chen, Yelong, Chen, Chuangzhen, Guo, Huancheng, Zhou, Chunbin, Wang, Hu, Liu, Zhaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898340/
https://www.ncbi.nlm.nih.gov/pubmed/36334221
http://dx.doi.org/10.1007/s10585-022-10192-5