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PITX1 suppresses osteosarcoma metastasis through exosomal LINC00662-mediated M2 macrophage polarization
Paired-like homeodomain transcription factor 1 (PITX1) is frequently downregulated in cancers, including osteosarcoma (OS). However, its role in OS remains unknown. Therefore, we aimed to explore the functions and potential mechanisms of PITX1 in OS malignant progression. Elevated PITX1 suppressed O...
Autores principales: | Zhang, Ying, Chen, Yelong, Chen, Chuangzhen, Guo, Huancheng, Zhou, Chunbin, Wang, Hu, Liu, Zhaoyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898340/ https://www.ncbi.nlm.nih.gov/pubmed/36334221 http://dx.doi.org/10.1007/s10585-022-10192-5 |
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