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Evaluation of Neonatal and Paediatric Vancomycin Pharmacokinetic Models and the Impact of Maturation and Serum Creatinine Covariates in a Large Multicentre Data Set

BACKGROUND AND OBJECTIVE: Infants and neonates present a clinical challenge for dosing drugs with high interindividual variability due to these patients’ rapid growth and the interplay between maturation and organ function. Model-informed precision dosing (MIPD), which can account for interindividua...

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Detalles Bibliográficos
Autores principales:	Hughes, Jasmine H., Tong, Dominic M. H., Faldasz, Jonathan D., Frymoyer, Adam, Keizer, Ron J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898357/ https://www.ncbi.nlm.nih.gov/pubmed/36404388 http://dx.doi.org/10.1007/s40262-022-01185-4

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