Genetic and modifiable risk factors combine multiplicatively in common disease

BACKGROUND: The joint contribution of genetic and environmental exposures to noncommunicable diseases is not well characterized. OBJECTIVES: We modeled the cumulative effects of common risk alleles and their prevalence variations with classical risk factors. METHODS: We analyzed mathematically and s...

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Detalles Bibliográficos
Autores principales: Pang, Shichao, Yengo, Loic, Nelson, Christopher P., Bourier, Felix, Zeng, Lingyao, Li, Ling, Kessler, Thorsten, Erdmann, Jeanette, Mägi, Reedik, Läll, Kristi, Metspalu, Andres, Mueller-Myhsok, Bertram, Samani, Nilesh J., Visscher, Peter M., Schunkert, Heribert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898372/
https://www.ncbi.nlm.nih.gov/pubmed/35987817
http://dx.doi.org/10.1007/s00392-022-02081-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898372/
https://www.ncbi.nlm.nih.gov/pubmed/35987817
http://dx.doi.org/10.1007/s00392-022-02081-4

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