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Upregulated GPRC5A disrupting the Hippo pathway promotes the proliferation and migration of pancreatic cancer cells via the cAMP-CREB axis

BACKGROUND: Pancreatic cancer has a high mortality rate worldwide, and is predicted to be third leading cause of death in the near future. However, the regulatory mechanisms that inhibit the progression of pancreatic cancer remain elusive. Currently, exploring the function and mechanisms of GPCRs (G...

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Detalles Bibliográficos
Autores principales: Fang, Weidan, Yu, Xin, Deng, Jun, Yu, Bin, Xiong, Jianping, Ma, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898488/
https://www.ncbi.nlm.nih.gov/pubmed/36735162
http://dx.doi.org/10.1007/s12672-023-00626-1