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Upregulated GPRC5A disrupting the Hippo pathway promotes the proliferation and migration of pancreatic cancer cells via the cAMP-CREB axis
BACKGROUND: Pancreatic cancer has a high mortality rate worldwide, and is predicted to be third leading cause of death in the near future. However, the regulatory mechanisms that inhibit the progression of pancreatic cancer remain elusive. Currently, exploring the function and mechanisms of GPCRs (G...
Autores principales: | Fang, Weidan, Yu, Xin, Deng, Jun, Yu, Bin, Xiong, Jianping, Ma, Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898488/ https://www.ncbi.nlm.nih.gov/pubmed/36735162 http://dx.doi.org/10.1007/s12672-023-00626-1 |
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