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Enrichment of human embryonic stem cell-derived V3 interneurons using an Nkx2-2 gene-specific reporter

V3 spinal interneurons are a key element of the spinal circuits, which control motor function. However, to date, there are no effective ways of deriving a pure V3 population from human pluripotent stem cells. Here, we report a method for differentiation and isolation of spinal V3 interneurons, combi...

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Detalles Bibliográficos
Autores principales: Berzanskyte, Ieva, Riccio, Federica, Machado, Carolina Barcellos, Bradbury, Elizabeth J., Lieberam, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898512/
https://www.ncbi.nlm.nih.gov/pubmed/36737643
http://dx.doi.org/10.1038/s41598-023-29165-z