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Enrichment of human embryonic stem cell-derived V3 interneurons using an Nkx2-2 gene-specific reporter
V3 spinal interneurons are a key element of the spinal circuits, which control motor function. However, to date, there are no effective ways of deriving a pure V3 population from human pluripotent stem cells. Here, we report a method for differentiation and isolation of spinal V3 interneurons, combi...
Autores principales: | Berzanskyte, Ieva, Riccio, Federica, Machado, Carolina Barcellos, Bradbury, Elizabeth J., Lieberam, Ivo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898512/ https://www.ncbi.nlm.nih.gov/pubmed/36737643 http://dx.doi.org/10.1038/s41598-023-29165-z |
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