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CCN3/NOV promotes metastasis and tumor progression via GPNMB-induced EGFR activation in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. TNBC patients typically exhibit unfavorable outcomes due to its rapid growth and metastatic potential. Here, we found overexpression of CCN3 in TNBC patients. We identified that CCN3 knockdown diminished cancer ste...

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Detalles Bibliográficos
Autores principales: Son, Seogho, Kim, Hyungjoo, Lim, Hogeun, Lee, Joo-hyung, Lee, Kyung-min, Shin, Incheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898537/
https://www.ncbi.nlm.nih.gov/pubmed/36737605
http://dx.doi.org/10.1038/s41419-023-05608-3